User Profile Service is considered to be the most complex service to setup but it all depend on the Active Directory structure, if its a single Forest then it will be simple but get complex when an organization have multiple Active Directory Forests. Please read this guide http://www.harbar.net/articles/sp2010ups.aspx before proceeding (the service has not changed in SharePoint 2010, SharePoint 2013 and SharePoint 2016). Check details on Installation and configuration of SharePoint 2016 and WFEs.

Follow bellow steps to provision the User Profile Service.

1- First setup the needed Web Applications

2- Setup the needed Accounts

3- Setup the needed access levels for the accounts

4- Launch Internet Explorer using elevated privileges.

5- Create two web applications (intranet.organizationname.com and My.organizationname.com)

6- Open SharePoint 2016 Central Administration, Go to Application Management >> Manage Service Applications >> Click on New >> Select User Profile Service Application.

SharePoint 2016 User Profile Service Application

7- Enter Application pool details, use any existing or create a new application pool.

8- In Profile Database section, use SQL alias for Database Server, SP_Profile for Database Name and Windows authentication for Database authentication. Leave Failover Server setting as is.

9- In Synchronization Database section, use SQL alias for Database Server, SP_Sync for Database Name and Windows authentication for Database authentication. Leave Failover Server setting as is.

10- In Social Tagging Database section, use SQL alias for Database Server, SP_Social for Database Name and Windows authentication for Database authentication. Leave Failover Server setting as is.

11- In Profile Synchronization Instance section, select SPWFE01 (Name of Web Front End server or standalone server name if single server installation).

12- Add the mysite web application URL (My.organizationname.com).

13- In My Site Managed Path section, enter /personal

14- In Site Naming Format section, select User name (resolve conflicts by using domain_username)

15- Select Yes in Default Proxy Group section.

16- Select Use on-premise SharePoint social functionality in Yammer Integration section.

17- Click Create to create User Profile Service Application.

18- After User Profile Service Application is created, we need to start User Profile Service and User Profile Synchronization Service on Manage Services on server Go to Application Management >> Manage services on server. Switch to front end 1 server from Server drop down from top right corner of the page.

Adnan, a distinguished professional, boasts an impressive track record as a Microsoft MVP, having achieved this prestigious recognition for the eighth consecutive year since 2015. With an extensive career spanning over 18 years, Adnan has honed his expertise in various domains, notably excelling in SharePoint, Microsoft 365, Microsoft Teams, the .Net Platform, and Microsoft BI. Presently, he holds the esteemed position of Senior Microsoft Consultant at Olive + Goose. Notably, Adnan served as the MCT Regional Lead for the Pakistan Chapter from 2012 to 2017, showcasing his leadership and commitment to fostering growth within the tech community. His journey in the realm of SharePoint spans 14 years, during which he has undertaken diverse projects involving both intranet and internet solutions for both private and government sectors. His impact has transcended geographical boundaries, leaving a mark on projects in the United States and the Gulf region, often collaborating with Fortune 500 companies. Beyond his roles, Adnan is a dedicated educator, sharing his insights and knowledge as a trainer. He also passionately advocates for technology, frequently engaging with the community through speaking engagements in various forums. His multifaceted contributions exemplify his dedication to the tech field and his role in driving its evolution.

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